NodMutDB

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since 4/20/2004

Last updated 10/01/09

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Mutant Detail

Mutant Detail:

Mutant Symbol	MtHAP2-1 miR169-a
Allele Symbol	MtHAP2-1 miR169-a
Gene and Mutation Location	MtHAP2-1 (overexpression of miR169-a)
Symbiotic Phenotype Brief	Bar-Bad-Nod+-Fix-
Phenotype Detail	The nodulation phenotype of MtHAP2-1 miR169 was remarkably similar to that observed with an MtHAP2-1 RNAi construct. Nodulation was delayed and nodule development process was significantly altered.
Single gene targeted?	yes
Extra Information	miR169 cleaves MtHAP2-1 in planta and MtHAP2-1 and the MtmiR169-a are oppositely regulated during nodulation
Mutagenesis Method	microRNA
Mutant Class	Nod+Fix-
Allelism
The earliest development stage known to be affected	N/A
Wildtype Line	Jemalong A17

References:

Authors	Year	Title	Locator
Combier JP, Frugier F, de Billy F, Boualem A, El-Yahyaoui F, Moreau S, Vernie T, Ott T, Gamas P, Crespi M and Niebel A	2006	MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula	Genes Dev. 20(22):3084-8

Curation Information:

Data entered by	Chunhong Mao (12/15/2006)
Final verification status	to be verified